Deion Sanders faces his toughest season in Colorado

The 2025 season has turned into a monumental challenge for Deion Sanders, known nationwide as Coach Prime. What began as a media-fueled revolution in Colorado—with the Buffaloes gaining national attention—now feels shaky. Painful defeats and health concerns have cast a shadow over the coach’s momentum. On top of that, rumors of institutional changes could shift the direction of the entire program.

After a promising win over No. 22 Iowa State, Deion Sanders and the Buffaloes were crushed 53-7 by Utah. It was the worst margin in the 72-year history of the rivalry. With a 3-5 record (1-4 in the Big 12), the early optimism has faded. Questions about Sanders’ future are growing louder.

Health vs. Scoreboard

But the discussion goes beyond the scoreboard. According to Marca, Deion Sanders’ health is a major factor. In 2025, he revealed a bladder cancer diagnosis that required major surgery. Though he’s recovering, he continues to battle blood clots and chronic pain. His resilience stands out—he even wrote his will during treatment, underscoring the seriousness of his condition.

 

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Una publicación compartida de @COACHPRIME (@deionsanders)

Another key piece is institutional support. Rick George, Colorado’s athletic director, has been a crucial ally for Deion Sanders, giving him the autonomy to build his vision freely. However, rumors of George’s early retirement are raising concerns. Analysts like Bruce Feldman and Kevin Borba point out that few programs offer the kind of backing Sanders enjoys in Boulder. Losing that support could destabilize the foundation he relies on.

Strategy and accountability

On the tactical side, Deion Sanders has shown self-awareness. He admitted that Utah’s Kyle Whittingham outcoached him, proving that his competitive nature doesn’t prevent him from taking responsibility. With three of the final four games now must-win to qualify for a bowl, the margin for error is razor-thin.

Deion Sanders didn’t shy away from saying @CUBuffsFootball “got their butts kicked tonight”, losing 53-7 to Utah. pic.twitter.com/NuAFEJ9laZ

— FOX College Football (@CFBONFOX) October 26, 2025

Off the field, Coach Prime is fighting a more complex battle. He’s trying to maintain leadership while managing his health, the team’s performance, and the potential loss of his strongest institutional support. Deion Sanders remains determined, but the circumstances around him may ultimately decide whether his time in Colorado continues or ends sooner than expected.

One thing is clear: Deion Sanders still inspires. But in Boulder, Prime’s future isn’t just about football—it’s about everything surrounding it.